Narsihmulu Cheryala

I received my Ph.D. in Synthetic Organic Chemistry with the specialization of natural products synthesis and development new synthetic methodologies. I have over 15 years of experience in academic and CRO medicinal chemistry programs including anti-viral, anti-cancer, anti-microbial, epilepsy and male contraception with a focus of small molecules design and synthesis.

American Chemical Society (ACS) – Organic and Medicinal Chemistry Division

Organic and medicinal chemistry

Siegel, R. A.; Kapoor, M.; Cheryala, N.; Georg, G. I.; Cloyd, J. C. Therapeutic compounds and formulations for intranasal delivery. WO2016149540A1, 2016. Filed March 18, 2015. Published September 22, 2016.

1. Rautiola, D.; Maglalang, P. D.; Cheryala, N.; Nelson, K. M.; Georg, G. I.; Fine, J. M.; Svitak, A. L.; Faltesek, K. A.; Hanson, L. R.; Mishra, U.; Coles, L. D.; Cloyd, J. C.; Siegel, R. A., Intranasal Coadministration of a Diazepam Prodrug with a Converting Enzyme Results in Rapid Absorption of Diazepam in Rats. J Pharmacol Exp Ther 2019, 370, 796-805.
2. Kapoor, M.; Cheryala, N.; Rautiola, D.; Georg, G. I.; Cloyd, J. C.; Siegel, R. A., Chirally Pure Prodrugs and Their Converting Enzymes Lead to High Supersaturation and Rapid Transcellular Permeation of Benzodiazepines. J. Pharm. Sci. 2016, 105, 2365-2371.
3. Siegel, R. A.; Kapoor, M.; Cheryala, N.; Georg, G. I.; Cloyd, J. C., Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies. Epilepsy Behav 2015, 49, 347-350.