Purification and Analytical Compounding Services

Test tubes running down a track on large medical equipment

The ITDD Purification and Analytical Services Facility carries out a variety of small-molecule analyses and purifications on a regular basis including LC-MS, low resolution mass spectrometry (LRMS), preparative, reverse phase liquid chromatography, and NMR. These analyses are facilitated by on-site instruments that include a Waters UPLC, two Waters ZQ mass spectrometers, a Waters autopurification system, and a Bruker 400 MHz NMR spectrometer.


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  • Low-resolution mass spectrometry
  • Reverse-phase, preparative separations
  • NMR experiments (1H, 13C, others)
  • Compound plating and dispensing
  • Vial weighing

Additional Analytical Equipment

  • Autopol V Polarimeter
  • Perkin-Elmer IR Spectrophotometer
  • 785 Karl Fisher Titrino System

Core Capabilities

  • 400 MHz Bruker NMR
  • Autopol V Polarimeter
  • Waters Acquity uPLC with ZQ mass spectrometer
  • Waters Autopurification system with ZQ mass spectrometer
  • Perkin-Elmer IR Spectrophotometer
  • Waters Preparative and Analytical HPLC
  • 785 Karl Fischer Titrino System


Shameem Sultana Syeda, Ph.D.
Director, Lead and Probe Discovery Core
Telephone: 612-626-6864
[email protected]