About Scientific Services

Institute for Therapeutics Discovery and Development (ITDD): Translational Services

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Step 1a: Drug Discovery and Lead Optimization

  • Assay Development
  • High-Throughput Screening
    • Screening Library: over 300,000 compounds
  • High Content Screening
  • Fragment Based Screening
  • In Silico (virtual) Screening
  • Hit Characterization
    • Analytical, Biophysical, Biochemical, Cell-Based
  • X-Ray Crystallography*
    • *through collaborations

Step 1b: Drug Discovery and Lead Optimization

  • SAR by Commerce
  • Hit-to-Lead Development
  • Computational Drug Design
  • Drug-Like Properties Optimization
  • Efficacy & Pharmacokinetics
  • Prodrug Design

(Projects can enter at any stage)

Step 2: Pre-Clinical Research

Clinical Candidate Identified

  • Scale Up Drug Synthesis
  • Formulation Studies*
    • *through collaborations
  • CMC-Enabling Studies
    • Drug Synthesis (API)
    • Analytical Development
    • Process Development
    • Reference Standard
    • Stability Studies
  • GLP Batch Manufacturing
  • Safety Pharmacology

Step 3: Clinical Research

Investigational New Drug (IND) Filing

  • GMP Drug Manufacturing

(Available to internal and external investigators)